This subject investigates exercise metabolism and related genomics and proteomics in an integrated fashion. Covering: energy pathways; metabolic control; metabolism, oxygen consumption and respiratory quotient relationships; metabolic responses to acute and chronic exercise; pathway contributions to exercise; metabolic limitations to exercise; metabolic contributions to fatigue; metabolic acidosis, cellular and systemic implications of metabolic thresholds, conditions that can alter cellular metabolism. Whilst skeletal muscle metabolism is the primary focus, liver and adipose tissue metabolism are also considered as are anabolic pathways. Students will be exposed to basic biochemical assays of interest to the exercise physiologist.